What makes you feel HIGH? - Cannabis Chemistry - 420Reap
Last Updated: Apr 11 2021
Cannabis is a term that increasingly refers to weed or marijuana. It is a kind of antidepressant.
Antidepressant does not mean it instantly changes your environment, and you start feeling happy. Instead, it slows down the central nervous system and makes you feel satisfied.
Cannabis doses can have different effects, which can result to be either beneficial or harmful.
"Fact – Cannabis is also known as grass, pot, dope, herb, mull, buddha, ganja, stick, cones, buckets, hydro, joint, stick, skunk, and smoke, etc."
Cannabis is a kind of species from the Cannabaceae family of plants. The main active chemical in Cannabis is THC(delta-9 tetracannabinol), a chemical compound that is accountable for psychoactive effects that leads to a “high” experience when consumed.
Kindly mark the point that all the components of Cannabis are not psychoactive. A person can smoke the dried buds of Cannabis, called marijuana. The sticky excretion(hashish) of the plant can also be smoked(or eaten).
Remember, while Cannabis comes from a plant and is naturally occurring, it can still have robust effects(both positive and negative).
The effects are variable and directly depends on the cannabis dosage.
In most cases, the effects of Cannabis can be –
People consuming high cannabis quantities become numb or confused and may experience toxic psychosis – not knowing who they are, where they are, or what time it is. Marijuana is used for medical purposes, but it manipulates body and brain functions, which is harmful to a long term consume.
Naturally, Cannabinoids occur as acids. By heating them, it converts into a neutral form(the process is called decarboxylation).
These decarboxylated/neutral cannabinoids are open to interact with receptors in the endocannabinoid system, where they can easily alter the release of neurotransmitters in the brain.
Through past researches, more than 100 different plant cannabinoids are recorded in marijuana. But only a few cannabinoids produce desirable and beneficial effects for users.
Follow the below list to know about these cannabinoids :
THC is the most dominant psychoactive component of Cannabis. This compound interacts with the human body, unlike any other.
THC is the reason behind feeling "High" by cannabis consumers.
Its complex series of reactions bind the brain's nerve receptors, which gives a happy and relaxed sensation to the brain and body.
For many years, humans have been taking advantage of these reactions. THC is potent medicine for patients who suffer from chronic pain, insomnia, low appetite, etc.
Cannabidiol(CBD) is a non-psychoactive component of marijuana. It is present in high concentrations, though it is easy to extract from a cannabis plant.
CBD and THC possess the same molecular formula. A slight difference is how the atoms are arranged. This fact is responsible for the effect of CBD and THC on your body.
CBD vs. THC: What’s the Difference? To know more, read this article.
The Variety of medicinal and therapeutic effects caused by marijuana are because of cannabidiol(CBD).
Unlike THC and other cannabinoids, CBD is legal almost everywhere. Considering its medical applications, cultivating CBD heavy-strains has become a priority in the industry.
For medical cannabis patients, cannabidiol can reduce mood disorders, inflammation, relieve pain, and stop seizures. For marijuana growers, CBD can help balance THC levels and smooth the edge of an extreme high.
Just like CBD, Cannabigerolic is non-psychoactive. This compound is a middle bridge to both CBD and THC. As soon as CBG appears, either it gets converted to CBD or THC.
Plant scientists have figured out factors that define which path CBG will take. Based on the research, cannabinoid production can be manipulated, leading to marijuana production with high CBD and low THC or vice versa.
Additionally, CBG has shown many medical benefits. Researches suggest that it could help in the treatment of cancer and various bladder and bowel diseases.
THCV is a crossbreed of CBD and THC. From CBD, it takes its modulating powers.
Tetrahydrocannabivarin can diminish the effect of too high. But at higher doses, THCV acts as a psychoactive stimulant. It can also intensify the euphoria THC causes.
The only problem with THCV is that it occurs in trace amounts in herbaceous Cannabis.
Fact: "Regular use of THCV may decrease your appetite."
If you want to read THCV benefits and where you can find THCV? – Read this
CBDV is also a non-psychoactive element. This cannabinoid is found in cannabis strains having high CBD concentrations.
Researchers found CBDV as a good alternative to CBD to cure clinical disorders. Current medical cannabis research has found CBDV as a robust anti-convulsant. It means CBDV can help reduce the occurrence of seizures for epilepsy patients.
Additionally, It is claimed that the compound can be used as an anti-nausea medicine.
CBC is a less-known cannabinoid but still crucial from a therapeutic perspective. It is earning popularity as an anxiety reducer. But researchers are always looking for a good reason to continue looking into its potential as a medicine.
Like THC and CBD, CBC has the same origin as cannabigerolic acid(CBGA). The cannabis plant produces CBGA. The specific plant enzyme converts CBGA to a cannabichromene carboxylic acid (CBCA). After exposure to heat and UV rays, Cannabichromene (CBC) gets prepared.
CBC can also be used for medical purposes. It can be a potent cancer fighter and helps to cure pain, acne.
Fact: "In 2013 mouse study, It was concluded that CBC has a positive effect on neural stem progenitor cells (NSPCs) - a cell essential to healthy brain function."
The effects of inhaled Cannabis can be observed within minutes and reach to peak within 10-3 0 minutes. This high experience stays for 2 to 3 hours.
Edible Cannabis, which has high THC levels, takes much more time to reach full effect as the gastrointestinal tract absorbs it—effects of edible Cannabis last upto 15 to 16 hours.
If you are dabbing a highly concentrated form of marijuana, then high stage kicks instantly.
Many scientific pieces of research have proven that marijuana can magically benefit in numerous medical conditions. Even the patients suffering from chronic diseases declare extremely positive health benefits of marijuana.
Fact : "In the 19th century, cannabis was introduced for therapeutic use in Western Medicine." - Source : Wikipedia
In most common cases, medical marijuana is used to cure severe or long term pain, nausea, and vomiting due to cancer treatments and painful muscle spasms.
However, there are other medical conditions for which the patient uses medical Cannabis.
Many studies found and described what people suffering from SCI said for years. Patients said that cannabis helped them in many impactful ways. While some people may not figure any benefit but many with spinal cord injury get benefitted.
There have been many studies in the last 20 years in different countries, they concluded THC and CBD as the most efficient cannabinoids in weed, can help people suffering from paralysis.
Cannabis may aid weight loss because of Cannabidiol(CBD) cannabinoid present in it. The effects of CBD in the body is because it can directly affect the body's natural endocannabinoid system. This natural system has two cannabinoid receptors called CB1 and CB2. These receptors respond to different chemicals in the body.
CBD works to activate these receptors and help the person to lose weight and other critical metabolic functions.
Medical cannabis laws first appeared in the second half of the 1990s. Weed works as magic for cancer patients, helps to relieve the harsh nauseating effects of chemotherapy.
Note: Chemotherapy is a drug treatment that uses robust chemicals to kill fast growing cells in the body. It is most often used to cure cancer patients.
In past years, many people suffering from epilepsy claimed that marijuana stops their seizures. Mainly, the presence of THC and CBD is responsible for the medical properties of cannabis. However, researchers are still going to answer whether a drug formulation of CBD can help control seizures.
PTSD causes chronic problems like nightmares, stupendous emotions, panic attacks, and self-destructive behavior. Many PTSD patients continue to report that cannabis helped them alot.
Two recent studies point to the way cannabis can help treat PTSD. One shows how cannabis controls the amygdala activities (the brain part that responds to fear). Other studies indicate cannabinoids in marijuana can help to erase traumatic memories.
MS is a disease that attacks your brain, spinal cord, and nerves. The weed plant has multiple chemicals that can affect the body and mind.
An authoritative national group of scientific institutions found that marijuana can help in stiffness and muscle spasms common in multiple sclerosis patients.
HIV patients use marijuana not to treat the virus itself but to cure HIV related symptoms like weight loss, low appetite, and nerve pain.
The primary treatment for HIV is antiretroviral therapy(ART).
"Glaucoma is a disease of the optic nerve, the cable that carries visual information from the eye to the brain. Damage to the optic nerve from glaucoma can result in vision loss and blindness."
Smoking marijuana is considered as a treatment for glaucoma as it lowers eye pressure. Marijuana's effect on eye pressure only lasts for 3-4 hours. This means you have to smoke 6-9 times a day to lower the eye pressure.
Numerous research on smoked marijuana found that it can help treat severe nausea and vomiting caused by cancer chemotherapy.
Few studies also found that inhaled marijuana can help in neuropathic pain caused by damaged nerves.
Neuropathic pain is a type of chronic pain caused by damage to the nervous system. THC cannabinoid present in cannabis binds the central nervous system. This manipulation blocks the pain nerve, and the person will feel relaxed.
But this is not a lifetime cure, and neuropathic patients need to take other prescriptions for their quick healing.
Medical marijuana comes in various forms, including tablet, oil, or liquid form.
Cannabis has been a part of human history for a millennium. Cannabis chemistry is much more complicated than any other plant. It is like a gift to humanity with amazing scientific secrets.
Complete cannabis chemistry includes proteins and enzymes, starches and carbohydrates, waxes, other oils, and many other plant chemicals.
In this article, we have discussed all the cannabinoids in which some are not psychoactive and have minimal medical value. But it's essential to know all the components discussed here.
They can significantly affect the color, flavor, and texture of concentrates and infused products.
The benefits of using cannabis are excellent whether you are using it for medical purposes or recreational use. Many people want to know what type of weed they are smoking or what is there in weed that makes them “high.” Reading this complete article will make you clear about what cannabis is actually made up of.
Though there are 100s of chemicals present in a cannabis plant. Some have positive, and some possess negative effects. In past scientific researches, only a few chemicals are known that we have discussed so far.
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